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Taxinine

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Chemical Structure| 3835-52-7 同义名 : -
CAS号 : 3835-52-7
货号 : A657125
分子式 : C35H42O9
纯度 : 98+%
分子量 : 606.703
MDL号 : -
存储条件：

粉末

液体 -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 Taxinine, a natural product isolated and purified from the seeds of Tuxus mairei., can inhibit the drug transport by P-glycoprotein in multidrug-resistant cells
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.65mL

0.33mL

0.16mL

8.24mL

1.65mL

0.82mL

16.48mL

3.30mL

1.65mL
参考文献

[1]Zhao X, Gu J, et al. Synthesis and biological evaluation of taxinine analogues as orally active multidrug resistance reversal agents in cancer. Bioorg Med Chem Lett. 2004 Sep 20;14(18):4767-70.

[2]Zhang S, Wang J, et al. An efficient conversion of taxinine to taxinine NN-1, an anticancer agent and a modulator of multidrug-resistant tumor cells. J Nat Prod. 2002 Dec;65(12):1786-92.