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Gentianine

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Chemical Structure| 439-89-4 同义名 : -
CAS号 : 439-89-4
货号 : A654676
分子式 : C10H9NO2
纯度 : 98+%
分子量 : 175.19
MDL号 : MFCD00801129
存储条件：

粉末

液体 -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 Gentianine, a natural product isolated and purified from the herbs of Trigonella foenum-graecum L., with potential anti-inflammatory action, might be at least partly based on the suppressed production of TNF-alpha and IL-6.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

5.71mL

1.14mL

0.57mL

28.54mL

5.71mL

2.85mL

57.08mL

11.42mL

5.71mL
参考文献

[1]Vaidya H, Goyal RK, Cheema SK. Anti-diabetic activity of swertiamarin is due to an active metabolite, gentianine, that upregulates PPAR-γ gene expression in 3T3-L1 cells. Phytother Res. 2013 Apr;27(4):624-7.

[2]Kwak WJ, Kim JH, et al. Effects of gentianine on the production of pro-inflammatory cytokines in male Sprague-Dawley rats treated with lipopolysaccharide (LPS). Biol Pharm Bull. 2005 Apr;28(4):750-3.