产品说明书

Licoflavonol

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Chemical Structure| 60197-60-6 同义名 : -
CAS号 : 60197-60-6
货号 : A652604
分子式 : C20H18O6
纯度 : 98+%
分子量 : 354.353
MDL号 : -
存储条件:

粉末

液体 -20°C:3-6个月-80°C:12个月

溶解度 : -
动物实验配方:
生物活性
描述 Licoflavonol, a natural product isolated and purified from the roots of Glycyrrhiza uralensis, exhibits a strong inhibitory effect on the secretion of the SPI-1 effector proteins via regulating the transcription of the SicA/InvF genes, and the transportation of the effector protein SipC. Thus, it is a natural inhibitor of Salmonella T3SS, could be a promising candidate for type of anti-virulence drugs.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.82mL

0.56mL

0.28mL

14.11mL

2.82mL

1.41mL

28.22mL

5.64mL

2.82mL

参考文献

[1]Guo Z, Li X, et al. Licoflavonol is an inhibitor of the type three secretion system of Salmonella enterica serovar Typhimurium. Biochem Biophys Res Commun. 2016 Sep 2;477(4):998-1004.

[2]Wang Q, Qian Y, et al. Metabolites identification of bioactive licorice compounds in rats. J Pharm Biomed Anal. 2015 Nov 10;115:515-22.