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Chemical Structure| 1422253-38-0 同义名 : PRI-724;C-82 prodrug;ICG-001 analog
CAS号 : 1422253-38-0
货号 : A650610
分子式 : C33H35N6O7P
纯度 : 99%+
分子量 : 658.641
MDL号 : MFCD12196918
存储条件:

粉末 Sealed in dry,2-8°C

液体 -20°C:3-6个月-80°C:12个月

溶解度 : -
动物实验配方:
生物活性
靶点
  • p300/CBP

描述 PRI-724 is a selective inhibitor of the CBP/β-catenin interaction.
临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点
NCT01606579 Acute Myeloid Leukemia ... 展开 >> Chronic Myeloid Leukemia 收起 << Phase 1 Phase 2 Completed - United States, Georgia ... 展开 >> Emory University / Winship Cancer Institute Atlanta, Georgia, United States, 30322 United States, Massachusetts University of Massachusetts Medical Center Worcester, Massachusetts, United States, 01655 United States, New Mexico New Mexico Cancer Care Alliance Albuquerque, New Mexico, United States, 87106 United States, North Carolina Duke University Medical Center Durham, North Carolina, United States, 27710 United States, Ohio Ohio State University Columbus, Ohio, United States, 43210-1267 United States, Texas University of Texas M.D. Anderson Cancer Center Houston, Texas, United States, 77030 收起 <<
NCT02195440 Hepatitis C Virus-infected Cir... 展开 >>rhosis 收起 << Phase 1 Completed - Japan ... 展开 >> Tokyo metropolitan Komagome Hospital Tokyo, Japan 收起 <<
NCT02413853 Colorectal Adenocarcinoma ... 展开 >> Stage IVA Colorectal Cancer Stage IVB Colorectal Cancer 收起 << Phase 2 Withdrawn(Study drug supply is... 展开 >>sues) 收起 << November 2018 United States, California ... 展开 >> USC Norris Comprehensive Cancer Center Los Angeles, California, United States, 90033 收起 <<
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.52mL

0.30mL

0.15mL

7.59mL

1.52mL

0.76mL

15.18mL

3.04mL

1.52mL