产品说明书
Tanshinone IIB
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同义名 : | - |
| CAS号 : | 17397-93-2 | |
| 货号 : | A642457 | |
| 分子式 : | C19H18O4 | |
| 纯度 : | 98+% | |
| 分子量 : | 310.34 | |
| MDL号 : | MFCD00238691 | |
| 存储条件： |
粉末 Sealed in dry,2-8°C 液体 -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : | - | |
| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Tanshinone IIB (TSB), a natural product isolated and purified from the roots of Salvia miltiorrhiza, can significantly inhibit the DNA laddering, cytotoxicity and apoptosis of rat cortical neurons induced by staurosporine in a concentration-dependent manner. TSB also suppresses the elevated Bax protein and decreased bcl-2 and caspase-3 proteins induced by staurosporine in rat cortical neurons, and is effective in reducing stroke-induced brain damage and may represent a drug candidate for further development. | ||
| 临床研究 | |||||
|---|---|---|---|---|---|
| NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
| NCT02200978 | Childhood Acute Promyelocytic ... 展开 >>Leukemia 收起 << | Phase 4 | Recruiting | September 2022 | China, Guangdong ... 展开 >> The First Affiliated Hospital of Sun Yat-Sen University Recruiting Guangzhou, Guangdong, China, 510080 Contact: Xue-Qun Luo, professor L-xuequn@126.com Principal Investigator: Xue-Qun Luo, professor 收起 << |
| NCT01452477 | Polycystic Ovary Syndrome | Not Applicable | Unknown | July 2014 | China, Heilongjiang ... 展开 >> Heilongjiang University of Chinese Medicine Recruiting Harbin, Heilongjiang, China, 150040 Contact: Wenjuan Shen, doctor +86-045182118464 shenwenjuankx@163.com Contact: Yuehui Zhang, doctor +86-045182118464 manbingPCOS@163.com Principal Investigator: Wenjuan Shen, doctor China, Jiangsu Huaian Maternal and Child Health Hospital Recruiting Huaian, Jiangsu, China, 223001 Contact: Huiying Xue, Scholar +8613505238015 haxuehuiying@126.com Principal Investigator: Huiying Xue, bachlor Lianyungang Maternal and Child Health Hospital Active, not recruiting Lianyungang, Jiangsu, China, 222000 China, Jiangxi JiangXi University of Traditional Chinese Medicine Completed Nanchang, Jiangxi, China, 330000 收起 << |
| NCT02524964 | Left Ventricular Remodeling ... 展开 >> Acute Myocardial Infarction 收起 << | Phase 4 | Unknown | July 2017 | China, Guangdong ... 展开 >> Guangdong Provincial Hospital of Chinese Medicine Recruiting Guangzhou, Guangdong, China, 510120 Contact: Minzhou Zhang, Dr. 86-20-81887233 ext 32801 minzhouzhang@yeah.net Contact: Liheng Guo, Dr. 86-8187236 ext 32907 lihengguo1@yeah.net 收起 << |
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
3.22mL 0.64mL 0.32mL |
16.11mL 3.22mL 1.61mL |
32.22mL 6.44mL 3.22mL |
| 参考文献 |
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