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L-Sulforaphane

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Chemical Structure| 142825-10-3 同义名 : (R)-Sulforaphane
CAS号 : 142825-10-3
货号 : A634288
分子式 : C6H11NOS2
纯度 : 98%
分子量 : 177.288
MDL号 : MFCD09039283
存储条件：

粉末 Inert atmosphere,Store in freezer, under -20°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(592.26 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 (R)-Sulforaphane (L-Sulforaphane) is a highly potent inducer of the Keap1/Nrf2/ARE pathway, with greater potency in inducing carcinogen-detoxifying enzyme systems in rat liver and lung than the S-isomer [1][2].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

5.64mL

1.13mL

0.56mL

28.20mL

5.64mL

2.82mL

56.41mL

11.28mL

5.64mL
参考文献

[1]De Nicola GR, et al. Novel gram-scale production of enantiopure R-sulforaphane from Tuscan black kale seeds. Molecules. 2014 May 27;19(6):6975-86.

[2]Abdull Razis AF, et al. The natural chemopreventive phytochemical R-sulforaphane is a far more potent inducer of the carcinogen-detoxifying enzyme systems in rat liver and lung than the S-isomer. Int J Cancer. 2011 Jun 15;128(12):2775-82.