产品说明书

Coumarin

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Chemical Structure| 91-64-5 同义名 : 2H-苯并吡喃-2-酮
CAS号 : 91-64-5
货号 : A633268
分子式 : C9H6O2
纯度 : 99+%
分子量 : 146.143
MDL号 : MFCD00006850
存储条件:

粉末 Keep in dark place,Inert atmosphere,Room temperature

液体 -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 105 mg/mL(718.48 mM),注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

H2O: 4 mg/mL(27.37 mM),配合低频超声助溶

动物实验配方:
生物活性
描述 Coumarin is a secondary phytochemical isolated and purified from the herbs of Melilotus officinalis with hepatotoxic and carcinogenic properties.
临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点
NCT01837758 - Completed - Germany ... 展开 >> Johann Wolfgang Goethe-University Frankfurt, Hessen, Germany, 60590 收起 <<
NCT02017197 Atrial Fibrillation Phase 4 Completed - Brazil ... 展开 >> Hospital São Paulo/Hospital Universitário da UNIFESP (University Hospital of UNIFESP) São Paulo, Brazil, 04024-002 收起 <<
NCT02066662 Atrial Fibrillation or Pulmona... 展开 >>ry Embolism Need of Long Term Oral Anticoagulation Therapy (OAT) Existent Coronary or Valvular Calcification, or Both and Agatston Score > 50 in at Least One Location 收起 << Phase 4 Active, not recruiting December 2019 Germany ... 展开 >> Hospital Coburg, Med. Clinic II for Internal Medicine and Cardiology Coburg, Bavaria, Germany, 96450 University Hospital Aachen, Department of Cardiology Aachen, North Rhine Westphalia, Germany, 52074 St.-Antonius-Hospital Eschweiler, Internal Medicine Eschweiler, North Rhine Westphalia, Germany, 52249 收起 <<
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

6.84mL

1.37mL

0.68mL

34.21mL

6.84mL

3.42mL

68.43mL

13.69mL

6.84mL

参考文献

[1]Xi GL, Liu ZQ. Coumarin-fused coumarin: antioxidant story from N,N-dimethylamino and hydroxyl groups. J Agric Food Chem. 2015 Apr 8;63(13):3516-23.

[2]Akoudad S, Darweesh SK, et al. Use of coumarin anticoagulants and cerebral microbleeds in the general population. Stroke. 2014 Nov;45(11):3436-9.