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Pierreione B

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Chemical Structure| 1292766-21-2 同义名 : -
CAS号 : 1292766-21-2
货号 : A629931
分子式 : C26H28O7
纯度 : 98+%
分子量 : 452.496
MDL号 : MFCD20275019
存储条件：

粉末

液体 -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 Pierreione B, a natural product isolated and purified from the leaves and twigs of Antheroporum pierrei, is an inhibitor of mTOR signaling with strong anticancer activity, and demonstrates solid tumor selectivity with minimal cytotoxicity.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.21mL

0.44mL

0.22mL

11.05mL

2.21mL

1.10mL

22.10mL

4.42mL

2.21mL
参考文献

[1]Yan J, Zhou H, et al. Identification of two novel inhibitors of mTOR signaling pathway based on high content screening. Cancer Chemother Pharmacol. 2013 Oct;72(4):799-808.

[2]Gao S, Xu YM, et al. Pierreiones A-D, solid tumor selective pyranoisoflavones and other cytotoxic constituents from Antheroporum pierrei. J Nat Prod. 2011 Apr 25;74(4):852-6.