Vitamin K1
产品说明书
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同义名 : | 叶绿醌;维生素K1 ;Phylloquinone;Phytomenadione;Aquamephyton, Konakion, Phyllohydroquinone, Phylloquinone, Phytomenadione, Phytonadione;Alpha-Phylloquinone;3-Phytylmenadione;trans-Phylloquinone;ɑ-Phylloquinone;NSC 270681;Phytonadione;Phyllohydroquinone |
| CAS号 : | 84-80-0 | |
| 货号 : | A627922 | |
| 分子式 : | C31H46O2 | |
| 纯度 : | 98% | |
| 分子量 : | 450.7 | |
| MDL号 : | MFCD00214063 | |
| 存储条件： |
Pure form Keep in dark place,Inert atmosphere,2-8°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 4 mg/mL(8.88 mM)，配合低频超声，并水浴加热至45℃助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO 无水乙醇: 50 mg/mL(110.94 mM)，注意：无水乙醇开封后，易挥发，也会吸收空气中的水分，导致溶解能力下降，请避免使用开封较久的乙醇 |
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| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Vitamin K1 a fat-soluble, naturally occurring vitamin required for blood coagulation and bone and vascular metabolism. Vitamin K1 treatment caused a significant antiproliferative effect and induced apoptosis in all the cell lines, with the involvement of the MAPK pathway. A significant polyamine decrease in addition to the antiproliferative and proapoptotic effects following vitamin K1 administration to colon cancer cell lines[1]. Vitamin K1 strengthens coagulation as measured by PT decrease and increases in the activity of vitamin K-dependent clotting factors and thrombin generation[2]. Maternal vitamin K supplementation increases milk vitamin K levels and can improve vitamin K status in breastfed infants who receive intramuscular vitamin K shortly after birth[3]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
2.22mL 0.44mL 0.22mL |
11.09mL 2.22mL 1.11mL |
22.19mL 4.44mL 2.22mL |
| 参考文献 |
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