产品说明书

Dehydro-α-lapachone

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Chemical Structure| 15297-92-4 同义名 : -
CAS号 : 15297-92-4
货号 : A627489
分子式 : C15H12O3
纯度 : 99%+
分子量 : 240.254
MDL号 : MFCD00022286
存储条件:

粉末 Sealed in dry,Store in freezer, under -20°C

液体 -20°C:3-6个月-80°C:12个月

溶解度 : -
动物实验配方:
生物活性
描述 Dehydro-alpha-lapachone, a natural product isolated and purified from the roots of Radermachera sinica with antifungal, antibacterial and antitumor activities, can be as a potential drug for reducing cancer metastasis and can inhibit vessel regeneration, interfere with vessel anastomosis, and limit plexus formation in zebrafish. It also can induce vascular pruning and growth delay in orthotopic mammary tumors in mice.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

4.16mL

0.83mL

0.42mL

20.81mL

4.16mL

2.08mL

41.62mL

8.32mL

4.16mL

参考文献

[1]Garkavtsev I, Chauhan VP, et al. Dehydro-alpha-lapachone, a plant product with antivascular activity. Proc Natl Acad Sci U S A. 2011 Jul 12;108(28):11596-601.

[2]Cho JY, Kim HY, et al. Dehydro-alpha-lapachone isolated from Catalpa ovata stems: activity against plant pathogenic fungi. Pest Manag Sci. 2006 May;62(5):414-8.