产品说明书

Buddleoside

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Chemical Structure| 480-36-4 同义名 : Linarine;Linarin;Linarigenin glycoside;Buddleoflavonoloside;Acacetin-7-O-rutinoside;Acaciin
CAS号 : 480-36-4
货号 : A627240
分子式 : C28H32O14
纯度 : 99%+
分子量 : 592.545
MDL号 : MFCD00151178
存储条件：

粉末 Sealed in dry,Store in freezer, under -20°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 250 mg/mL(421.91 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Linarin, a natural product isolated and purified from the herb of Uncaria sinensis (Oliv.) Havil., prevents a beta-induced neurotoxicity through the activation of PI3K/Akt, which subsequently inhibits GSK-3b and up-regulates Bcl-2.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.69mL

0.34mL

0.17mL

8.44mL

1.69mL

0.84mL

16.88mL

3.38mL

1.69mL
参考文献

[1]Kim SJ, Cho HI, et al. Protective effect of linarin against D-galactosamine and lipopolysaccharide-induced fulminant hepatic failure. Eur J Pharmacol. 2014 Sep 5;738:66-73.

[2]Feng X, Liu Y, et al. Effects of piperine on the intestinal permeability and pharmacokinetics of linarin in rats. Molecules. 2014 Apr 30;19(5):5624-33.