产品说明书

Alisol B 23-acetate

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Chemical Structure| 26575-95-1 同义名 : 泽泻醇B乙酸酯 ;Alisol B monoacetate;23-Acetylalismol B;Alisol B Acetate;23-O-Acetylalisol B
CAS号 : 26575-95-1
货号 : A624674
分子式 : C32H50O5
纯度 : 98%
分子量 : 514.736
MDL号 : MFCD00210473
存储条件：

粉末 Keep in dark place,Sealed in dry,2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 50 mg/mL(97.14 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Alisol B 23-acetate, a natural triterpenoid, produces protective effects against EE-induced cholestasis, due to FXR-mediated gene regulation.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.94mL

0.39mL

0.19mL

9.71mL

1.94mL

0.97mL

19.43mL

3.89mL

1.94mL
参考文献

[1]Meng Q, Chen X, et al. Protective effects of alisol B 23-acetate from edible botanical Rhizoma alismatis against carbon tetrachloride-induced hepatotoxicity in mice. Food Funct. 2015 Apr;6(4):1241-50.

[2]Meng Q, Chen XL, et al. Alisol B 23-acetate protects against ANIT-induced hepatotoxity and cholestasis, due to FXR-mediated regulation of transporters and enzymes involved in bile acid homeostasis. Toxicol Appl Pharmacol. 2015 Mar 15;283(3):178-86.