产品说明书

Betamethasone dipropionate

Print
Chemical Structure| 5593-20-4 同义名 : 17,21-二丙酸倍他米松酯 ;Betamethasone 17,21-dipropionate;SCH 11460;Luxiq;Diprosone;Diprolene AF;Diprolene;BetaVal;Alphatrex
CAS号 : 5593-20-4
货号 : A624424
分子式 : C28H37FO7
纯度 : 99+%
分子量 : 504.588
MDL号 : MFCD00133140
存储条件:

粉末 Sealed in dry,Room Temperature

液体 -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 105 mg/mL(208.09 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

动物实验配方:

IP 2% DMSO+2% Tween80+40% PEG300+water 5 mg/mL clear

PO 0.5% CMC-Na 35 mg/mL suspension

生物活性
描述 Betamethasone dipropionate is a glucocorticoid steroid with anti-inflammatory and immunosuppressive abilities.
临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点
NCT03165825 Cervical Radiculopathy Phase 4 Withdrawn(funding) October 2019 -
NCT03196817 Carpal Tunnel Syndrome Phase 4 Active, not recruiting December 2017 Brazil ... 展开 >> Jesus Queiroz junior São Paulo, Brazil, 03325000 收起 <<
NCT02978976 Neonatal Respiratory Distress Phase 4 Recruiting May 2018 Egypt ... 展开 >> 11562 Recruiting Cairo, Egypt, 11562 Contact: Ahmed M KameL, M.D    01120022332    dr.ahmed.m.kamel@gmail.com 收起 <<
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.98mL

0.40mL

0.20mL

9.91mL

1.98mL

0.99mL

19.82mL

3.96mL

1.98mL

参考文献

[1]Yan R, Jiang S, et al. Topical calcipotriol/betamethasone dipropionate for psoriasis vulgaris: A systematic review. Indian J Dermatol Venereol Leprol. 2016 Mar-Apr;82(2):135-44.

[2]Leonardi C, Bagel J, et al. Efficacy and Safety of Calcipotriene Plus Betamethasone Dipropionate Aerosol Foam in Patients With Psoriasis Vulgaris--a Randomized Phase III Study (PSO-FAST). J Drugs Dermatol. 2015 Dec;14(12):1468-77.