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Boeravinone B

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Chemical Structure| 114567-34-9 同义名 : -
CAS号 : 114567-34-9
货号 : A622362
分子式 : C17H12O6
纯度 : 98+%
分子量 : 312.27
MDL号 : MFCD21608445
存储条件:

粉末 2-8°C

液体 -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 50 mg/mL(160.12 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

动物实验配方:
生物活性
描述 Boeravinone B is a natural product isolated and purified from the roots of Boerhaavia coccinea, exhibits significant anti-inflammatory activity (56.6% at 50 mg/kg) when evaluated in an in vivo carrageenan-induced rat paw model ,and is an efflux pump inhibitor, apart from inhibiting the MdeA mediated efflux, also significantly inhibit the biofilm formation of S. aureus, that may be used in combination with mupirocin for further development.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.20mL

0.64mL

0.32mL

16.01mL

3.20mL

1.60mL

32.02mL

6.40mL

3.20mL

参考文献

[1]Bhope SG, Gaikwad PS, et al. RP-HPLC method for the simultaneous quantitation of boeravinone E and boeravinone B in Boerhaavia diffusa extract and its formulation. Nat Prod Res. 2013;27(6):588-91.