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Ononin

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Chemical Structure| 486-62-4 同义名 : Ononoside;Formononetin 7-O-β-D-glucopyranoside;Ononin, Formononetin 7-O-β-D-Glucopyranoside, Formononetin Glucoside, Formononetin 7-O-Glucoside;Formononetin 7-O-glucoside;Formononetin glucoside
CAS号 : 486-62-4
货号 : A615450
分子式 : C22H22O9
纯度 : 98+%
分子量 : 430.405
MDL号 : MFCD03225479
存储条件：

粉末 Inert atmosphere,2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(243.96 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Ononin is an isoflavonoid isolated and purified from the herb of Ononis natrix L., can inhibit the growth of pathogen such as Enterococcus sp., Enterobacter sp. and can promote the growth of probiotics such as Bifidobacteria sp. and Lactobacilli sp., and has an effect on the expression of HIF-1 in a concentration-dependent manner, low concentration could elevate the expression of HIF-1 while high concentration down-regulated the expression.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.32mL

0.46mL

0.23mL

11.62mL

2.32mL

1.16mL

23.23mL

4.65mL

2.32mL
参考文献

[1]Zhang W, Jiang S, et al. [The interaction between ononin and human intestinal bacteria] . Yao Xue Xue Bao. 2014 Aug;49(8):1162-8. Chinese.

[2]Inderjit, Dakshini KM. Formononetin 7-O-glucoside (ononin), an additional growth inhibitor in soils associated with the weed,Pluchea lanceolata (DC) C.B. Clarke (Asteraceae). J Chem Ecol. 1992 May;18(5):713-8.