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Bis(NHS)PEG5

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Chemical Structure| 756526-03-1 同义名 : Bis-PEG5-NHS ester
CAS号 : 756526-03-1
货号 : A607408
分子式 : C22H32N2O13
纯度 : 98%
分子量 : 532.495
MDL号 : MFCD11041118
存储条件：

粉末 Inert atmosphere,Store in freezer, under -20°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(197.18 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Bis-PEG5-NHS ester, a PEG/Alkyl/ether-based PROTAC linker, is applicable in the construction of PROTACs. Moreover, it serves as a cleavable ADC linker in the synthesis of antibody-drug conjugates (ADCs) [1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.88mL

0.38mL

0.19mL

9.39mL

1.88mL

0.94mL

18.78mL

3.76mL

1.88mL
参考文献

[1]Hans-Georg Lerchen, et al. Prodrugs of cytotoxic active agents having enzymatically cleavable groups. WO2018114798A1.