产品说明书

Taraxasterol

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Chemical Structure| 1059-14-9 同义名 : -
CAS号 : 1059-14-9
货号 : A601522
分子式 : C30H50O
纯度 : 98+%
分子量 : 426.71
MDL号 : MFCD04039802
存储条件：

粉末 Sealed in dry,2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 1 mg/mL(2.34 mM)，配合低频超声，并水浴加热至45℃助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO

无水乙醇: 5 mg/mL(11.72 mM)，配合低频超声，并水浴加热至45℃助溶，注意：无水乙醇开封后，易挥发，也会吸收空气中的水分，导致溶解能力下降，请避免使用开封较久的乙醇
动物实验配方：
生物活性
描述 Taraxasterol is a natural product isolated and purified from the herbs of Taraxacum officinale with anti-inflammatory activity. Taraxasterol inhibits NO, PGE(2), TNF-α, IL-1β and IL-6 production in LPS-induced RAW 264.7 macrophages in a dose-dependent manner.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.34mL

0.47mL

0.23mL

11.72mL

2.34mL

1.17mL

23.44mL

4.69mL

2.34mL
参考文献

[1]Jiang SH, Ping LF, et al. Protective effect of taraxasterol against rheumatoid arthritis by the modulation of inflammatory responses in mice. Exp Ther Med. 2016 Dec;12(6):4035-4040.

[2]Wang Y, Li GH, et al. In vivo anti-inflammatory effects of taraxasterol against animal models. Afr J Tradit Complement Altern Med. 2016 Nov 23;14(1):43-51.