产品说明书

Benzoylmesaconine

Print
Chemical Structure| 63238-67-5 同义名 : Mesaconine 14-benzoate;14-Benzoylmesaconine
CAS号 : 63238-67-5
货号 : A599512
分子式 : C31H43NO10
纯度 : 98+%
分子量 : 589.67
MDL号 : MFCD01673475
存储条件：

粉末 Sealed in dry,2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(178.06 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Benzoylmesaconine is the most abundant component of Wutou decoction, which is widely used in China because of its therapeutic effect on rheumatoid arthritis.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.70mL

0.34mL

0.17mL

8.48mL

1.70mL

0.85mL

16.96mL

3.39mL

1.70mL
参考文献

[1]Dai PM, Wang Y, et al. Pharmacokinetic comparisons of benzoylmesaconine in rats using ultra-performance liquid chromatography-tandem mass spectrometry after administration of pure benzoylmesaconine and Wutou decoction. Molecules. 2014 Oct 17;19(10):16757-69.

[2]Ye L, Yang XS, Lu LL, Chen WY, Zeng S, Yan TM, Dong LN, Peng XJ, Shi J, Liu ZQ. Monoester-Diterpene Aconitum Alkaloid Metabolism in Human Liver Microsomes: Predominant Role of CYP3A4 and CYP3A5. Evid Based Complement Alternat Med. 2013;2013:941093.