产品说明书

N6-Cyclohexyladenosine

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Chemical Structure| 36396-99-3 同义名 : CHA
CAS号 : 36396-99-3
货号 : A598514
分子式 : C16H23N5O4
纯度 : 99%+
分子量 : 349.385
MDL号 : MFCD00036808
存储条件:

粉末 Keep in dark place,Sealed in dry,2-8°C

液体 -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 105 mg/mL(300.53 mM),注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

动物实验配方:
生物活性
描述 N6-Cyclohexyladenosine is a selective A1 receptor agonist (EC50 = 8.2 nM).
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.86mL

0.57mL

0.29mL

14.31mL

2.86mL

1.43mL

28.62mL

5.72mL

2.86mL

参考文献

[1]Asghari AA, Azarnia M, et al. Adenosine A1 receptor agonist, N6-cyclohexyladenosine, protects myelin and induces remyelination in an experimental model of rat optic chiasm demyelination; electrophysiological and histopathological studies. J Neurol Sci. 2013 Feb 15;325(1-2):22-8.

[2]Heidarianpour A, Sadeghian E, et al. Anticonvulsant effects of N6-cyclohexyladenosine microinjected into the CA1 region of the hippocampus on entorhinal cortex-kindled seizures in rats. Epileptic Disord. 2006 Dec;8(4):259-66.