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Tridecanoic Acid

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Chemical Structure| 638-53-9 同义名 : 十三烷酸 ;N-Tridecanoic acid;C13:0 Fatty acid;n-Tridecoic acid;Tridecylic acid;638-53-9
CAS号 : 638-53-9
货号 : A597584
分子式 : C13H26O2
纯度 : 98%
分子量 : 214.344
MDL号 : MFCD00002741
存储条件:

粉末 Sealed in dry,Room Temperature

液体 -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 105 mg/mL(489.87 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

动物实验配方:
生物活性
描述 Tridecanoic Acid is an endogenous metabolite and belongs to the class of organic compounds known as long-chain fatty acids. The product distribution of tridecanoic, tetradecanoic and pentadecanoic acid oxidation by Krac9955 favoured oxidation at the ω-4, ω-5 and ω-6 positions, respectively. Krac9955 preferably oxidised shorter fatty acids compared to Krac0936 with tridecanoic having the highest levels of product formation[1]. CYP505A30 (cytochrome P450/P450 reductase fusion enzyme) binds straight chain fatty acids (from ∼C10 to C20), with highest affinity for tridecanoic acid (KD = 2.7 μM) [2]. The fatty acids on mouse renin were partially exchangeable with free tridecanoic acid in solution, with the tridecanoic acid truly exchanged and not just adsorbed in addition to the fatty acids already present[3]. Tridecanoic acid (C13) showed attractance only at 10(-4) g dose while higher doses caused repellence. The identification of odoriferous acids (Tridecanoic acid) acts as potential attractants, repellents, or attraction inhibitors[4].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

4.67mL

0.93mL

0.47mL

23.33mL

4.67mL

2.33mL

46.65mL

9.33mL

4.67mL

参考文献

[1]Munday SD, Maddigan NK, Young RJ, Bell SG. Characterisation of two self-sufficient CYP102 family monooxygenases from Ktedonobacter racemifer DSM44963 which have new fatty acid alcohol product profiles. Biochim Biophys Acta. 2016;1860(6):1149‐1162

[2]Baker GJ, Girvan HM, Matthews S, et al. Expression, Purification, and Biochemical Characterization of the Flavocytochrome P450 CYP505A30 from Myceliophthora thermophila. ACS Omega. 2017;2(8):4705‐4724

[3]Poe M, Liesch JM. Mouse submaxillary gland renin contains a noncovalently attached fatty acid. J Biol Chem. 1983;258(16):9856‐9860

[4]Seenivasagan T, Guha L, Parashar BD, Agrawal OP, Sukumaran D. Olfaction in Asian tiger mosquito Aedes albopictus: flight orientation response to certain saturated carboxylic acids in human skin emanations. Parasitol Res. 2014;113(5):1927‐1932