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DOPE

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Chemical Structure| 4004-05-1 同义名 : dioleoylphosphatidylethanolamine;1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine;1,2-Dioleoyl-sn-glycero-3-Phosphoethanolamine 1,2-DOPE;1,2-DOPE;1,2-Dioleoyl-sn-glycero-3-PE
CAS号 : 4004-05-1
货号 : A593796
分子式 : C41H78NO8P
纯度 : 98%+
分子量 : 744.034
MDL号 : MFCD00057986
存储条件：

粉末 Keep in dark place,Inert atmosphere,Store in freezer, under -20°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

无水乙醇: 8 mg/mL(10.75 mM)，配合低频超声，并水浴加热至45℃助溶，注意：无水乙醇开封后，易挥发，也会吸收空气中的水分，导致溶解能力下降，请避免使用开封较久的乙醇
动物实验配方：
生物活性
描述 DOPE (dioleoylphosphatidylethanolamine) is a neutral co-lipid for cationic liposomes, and binding to cationic phospholipids improves the transfection efficiency of naked siRNA[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.34mL

0.27mL

0.13mL

6.72mL

1.34mL

0.67mL

13.44mL

2.69mL

1.34mL
参考文献

[1]Uemura Y, et al. The efficiency of lipid nanoparticles with an original cationic lipid as a siRNA delivery system for macrophages and dendritic cells.Pharm Dev Technol. 2019 Mar;24(3):263-268.