Seneciphylline

产品说明书

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Chemical Structure| 480-81-9 同义名 : 千里光非灵 ;NSC 30622
CAS号 : 480-81-9
货号 : A589859
分子式 : C18H23NO5
纯度 : 99+%
分子量 : 333.38
MDL号 : MFCD00221722
存储条件：

Pure form Keep in dark place,Inert atmosphere,2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 6 mg/mL(18 mM)，配合低频超声，并水浴加热至45℃助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Seneciphylline, a natural product isolated and purified from the herbs of Senecio scandens, can significantly increased the activities of epoxide hydrase and glutathione-S-transferase but cause reduction of cytochrome P-450 and related monooxygenase activities.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.00mL

0.60mL

0.30mL

15.00mL

3.00mL

1.50mL

30.00mL

6.00mL

3.00mL
参考文献

[1]Nuringtyas TR, Verpoorte R, et al. Toxicity of pyrrolizidine alkaloids to Spodoptera exigua using insect cell lines and injection bioassays. J Chem Ecol. 2014 Jun;40(6):609-16.

[2]Kakrani HK, Kalyani GA. Effect of seneciphylline and senecionine on hepatic drug metabolizing enzymes in rats. J Ethnopharmacol. 1984 Dec;12(3):271-8.