Germacrone
产品说明书
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同义名 : | (E,E)-Germacrone |
| CAS号 : | 6902-91-6 | |
| 货号 : | A578841 | |
| 分子式 : | C15H22O | |
| 纯度 : | 99%+ | |
| 分子量 : | 218.335 | |
| MDL号 : | MFCD00210050 | |
| 存储条件： |
Pure form Sealed in dry,2-8°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 105 mg/mL(480.91 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
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| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Germacrone, a natural product isolated and purified from the rhizoma of Curcuma wenyujin with anti-tumor activity, can inhibit the proliferation of breast cancer cell lines by inducing cell cycle arrest and apoptosis through mitochondria-mediated caspase pathway, and may be a potent chemopreventive drug candidate for liver cancer via regulating the expression of proteins related to G2/M cell cycle and apoptosis, and p53 and oxidative damage may play important roles in the inhibition of human hepatoma cells growth by germacrone. | ||
| 实验方案 | |||
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| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
4.58mL 0.92mL 0.46mL |
22.90mL 4.58mL 2.29mL |
45.80mL 9.16mL 4.58mL |
| 参考文献 |
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