产品说明书
Cortexolone
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同义名 : | 11-脱氧皮质醇;可托多松;脱氧可的松 ;Cortodoxone;11-Deoxycortisol;Cortisol, 11-deoxy-;NSC-18317;Substance S;SKF 3050;SK&F 3050;Reichstein's substance S |
| CAS号 : | 152-58-9 | |
| 货号 : | A576667 | |
| 分子式 : | C21H30O4 | |
| 纯度 : | 98% | |
| 分子量 : | 346.461 | |
| MDL号 : | MFCD00003662 | |
| 存储条件： |
粉末 Sealed in dry,Room Temperature 液体 -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 50 mg/mL(144.32 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
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| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Cortodoxone is a glucocorticoid steroid hormone that can be oxygenated to cortisol (Hydrocortisone). | ||
| 临床研究 | |||||
|---|---|---|---|---|---|
| NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
| NCT02760277 | Duchenne Muscular Dystrophy | Phase 2 | Completed | - | United States, California ... 展开 >> University of California Davis Davis, California, United States, 95616 United States, Florida University of Florida Gainesville, Florida, United States, 32611 Nemours Children's Hospital Orlando, Florida, United States, 32827 United States, Illinois Ann & Robert H. Lurie Children's Hospital Chicago, Illinois, United States, 60611 United States, North Carolina Duke University Durham, North Carolina, United States, 27710 United States, Texas University of Texas Southwestern Medical Center Dallas, Texas, United States, 75207 Australia Royal Children's Hospital Melbourne, Australia Sydney Children's Hospital Westmead, Australia Canada, Alberta Alberta Children's Hospital Calgary, Alberta, Canada, T3B 6A8 Israel Schneider Children's Medical Center Petah Tikwah, Israel, 49202 Sweden Queen Silvia Children's Hospital Gothenburg, Sweden, 41685 United Kingdom Newcastle upon Tyne Hospitals NHS Foundation Trust Newcastle upon Tyne, United Kingdom, NE7 7DN 收起 << |
| NCT03038399 | Duchenne Muscular Dystrophy | Phase 2 | Enrolling by invitation | January 2021 | United States, California ... 展开 >> University of California Davis Davis, California, United States, 95616 United States, Florida University of Florida Gainesville, Florida, United States, 32611 Nemours Children's Hospital Orlando, Florida, United States, 32827 United States, Illinois Ann & Robert H. Lurie Children's Hospital Chicago, Illinois, United States, 60611 United States, North Carolina Duke University Durham, North Carolina, United States, 27710 United States, Texas University of Texas Southwestern Medical Center Dallas, Texas, United States, 75207 Australia Royal Children's Hospital Melbourne, Australia Sydney Children's Hospital Westmead, Australia Canada, Alberta Alberta Children's Hospital Calgary, Alberta, Canada, T3B 6A8 Israel Schneider Children's Medical Center Petah Tikwah, Israel, 49202 Sweden Queen Silvia Children's Hospital Gothenburg, Sweden, 41685 United Kingdom Newcastle upon Tyne Hospitals NHS Foundation Trust Newcastle upon Tyne, United Kingdom, NE7 7DN 收起 << |
| NCT02760264 | Duchenne Muscular Dystrophy | Phase 2 | Completed | - | United States, California ... 展开 >> University of California Davis Davis, California, United States, 95616 United States, Florida University of Florida Gainesville, Florida, United States, 32611 Nemours Children's Hospital Orlando, Florida, United States, 32827 United States, Illinois Ann & Robert H. Lurie Children's Hospital Chicago, Illinois, United States, 60611 United States, North Carolina Duke University Durham, North Carolina, United States, 27710 United States, Texas University of Texas Southwestern Medical Center Dallas, Texas, United States, 75207 Australia Royal Children's Hospital Melbourne, Australia Sydney Children's Hospital Westmead, Australia Canada, Alberta Alberta Children's Hospital Calgary, Alberta, Canada, T3B 6A8 Israel Schneider Children's Medical Center Petah Tikvah, Israel, 49202 Sweden Queen Silvia Children's Hospital Gothenburg, Sweden, 41685 United Kingdom Newcastle upon Tyne Hospitals NHS Foundation Trust Newcastle upon Tyne, United Kingdom, NE7 7DN 收起 << |
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
2.89mL 0.58mL 0.29mL |
14.43mL 2.89mL 1.44mL |
28.86mL 5.77mL 2.89mL |
| 参考文献 |
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