产品说明书
SNIPER(ER)-110
 |
同义名 : | - |
| CAS号 : | 2241690-03-7 | |
| 货号 : | A575501 | |
| 分子式 : | C66H83N5O11 | |
| 纯度 : | 98% | |
| 分子量 : | 1122.392 | |
| MDL号 : | N/A | |
| 存储条件： |
粉末 液体 -20°C:3-6个月-80°C:12个月 |
|
| 溶解度 : | - | |
| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | SNIPER(ER)-110 is a nongenetic IAP-dependent protein eraser (SNIPER) targeting estrogen receptor α (ERα), induces ERα degradation and induces apoptosis in MCF-7 human breast cancer cells; inhibits the growth of MCF-7 tumor xenografts in mice more potently than the previously characterized SNIPER(ER)-87, preferentially recruits XIAP, rather than cIAP1, to degrade ERα. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
0.89mL 0.18mL 0.09mL |
4.45mL 0.89mL 0.45mL |
8.91mL 1.78mL 0.89mL |
