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DDR Inhibitor

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Chemical Structure| 1644069-80-6 同义名 : -
CAS号 : 1644069-80-6
货号 : A570083
分子式 : C23H20FN5O2
纯度 : 98%
分子量 : 417.436
MDL号 : MFCD31567545
存储条件：

粉末 Sealed in dry,Store in freezer, under -20°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 65 mg/mL(155.71 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 DDR Inhibitor is a potent discoidin domain receptor (DDR) inhibitor, with an IC50 of 3.3 nM for DDR2, and shows 53% inhibition on DDR1 at 1.5 nM.
临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点
NCT02516111 Chronic Periodontitis Phase 2 Phase 3 Completed - -
NCT02600520 Chronic Periodontitis Phase 2 Phase 3 Completed - -
NCT03404960 Pancreatic Adenocarcinoma Phase 1 Phase 2 Recruiting June 2021 United States, Pennsylvania ... 展开 >> University of Pennsylvania, Abramson Cancer Center Recruiting Philadelphia, Pennsylvania, United States, 19104 Contact: Danielle Karlson    215-220-9704    danielle.Karlson@uphs.upenn.edu    Principal Investigator: Kim Reiss Binder, MD 收起 <<
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.40mL

0.48mL

0.24mL

11.98mL

2.40mL

1.20mL

23.96mL

4.79mL

2.40mL