Scopolin

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Chemical Structure| 531-44-2 同义名 : 东莨菪甙 ;NSC 404560
CAS号 : 531-44-2
货号 : A556665
分子式 : C16H18O9
纯度 : 98+%
分子量 : 354.31
MDL号 : MFCD02259444
存储条件：

Pure form 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(296.35 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Scopolin, a natural product isolated and purified from the herb of Scopolia japonica, can reduce the clinical symptoms of rat AIA by inhibiting inflammation and angiogenesis,and this compound may be a potent agent for angiogenesis related diseases and can serve as a structural base for screening more potent synthetic analogs.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.82mL

0.56mL

0.28mL

14.11mL

2.82mL

1.41mL

28.22mL

5.64mL

2.82mL
参考文献

[1]Pan R, Dai Y, et al. Scopolin isolated from Erycibe obtusifolia Benth stems suppresses adjuvant-induced rat arthritis by inhibiting inflammation and angiogenesis. Int Immunopharmacol. 2009 Jul;9(7-8):859-69.

[2]Rollinger JM, Hornick A, et al. Acetylcholinesterase inhibitory activity of scopolin and scopoletin discovered by virtual screening of natural products. J Med Chem. 2004 Dec 2;47(25):6248-54.