Isofuranodiene

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Chemical Structure| 57566-47-9 同义名 : -
CAS号 : 57566-47-9
货号 : A549850
分子式 : C15H20O
纯度 : 98+%
分子量 : 216.32
MDL号 : -
存储条件:

Pure form

In solvent -20°C:3-6个月-80°C:12个月

溶解度 : -
动物实验配方:
生物活性
描述 Isofuranodiene, a natural product isolated and purified from the herbs of Chloranthus spicatus, has anticancer activity, by inhibiting the proliferation and inducing apoptosis in cancer cells, protects GalN/LPS-induced liver injury in SD rats, it may be a potential functional food ingredient for the prevention and treatment of liver diseases and can induce apoptosis in colon cancer cells in a time and concentration-dependent manner suggesting a potential role as models for the development of chemopreventive agents.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

4.62mL

0.92mL

0.46mL

23.11mL

4.62mL

2.31mL

46.23mL

9.25mL

4.62mL

参考文献

[1]Li W, Shi J, et al. Isofuranodiene, the main volatile constituent of wild celery (Smyrnium olusatrum L.), protects d-galactosamin/lipopolysacchride-induced liver injury in rats. Nat Prod Res. 2016;30(10):1162-5.

[2]Quassinti L, Maggi F, et al. Wild celery (Smyrnium olusatrum L.) oil and isofuranodiene induce apoptosis in human colon carcinoma cells. Fitoterapia. 2014 Sep;97:133-41.