产品说明书

Damnacanthal

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Chemical Structure| 477-84-9 同义名 : -
CAS号 : 477-84-9
货号 : A549543
分子式 : C16H10O5
纯度 : 98%
分子量 : 282.248
MDL号 : N/A
存储条件:

粉末 Inert atmosphere,Store in freezer, under -20°C

液体 -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 4 mg/mL(14.17 mM),配合低频超声,并水浴加热至45℃助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

动物实验配方:
生物活性
描述 Damnacanthal, a natural product isolated and purified from the fruit of Morinda citrifolia Linn., possesses anti-cancer property and can treat or prevent hepatocellular carcinoma through its inhibitory effects on the HGF/c-Met axis.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.54mL

0.71mL

0.35mL

17.71mL

3.54mL

1.77mL

35.43mL

7.09mL

3.54mL

参考文献

[1]Garcia-Vilas JA, Medina MA, et al. Damnacanthal inhibits IgE receptor-mediated activation of mast cells. Mol Immunol. 2015 May;65(1):86-93.

[2]Kim MH, Jeong HJ. Damnacanthal inhibits the NF-κB/RIP-2/caspase-1 signal pathway by inhibiting p56lck tyrosine kinase. Immunopharmacol Immunotoxicol. 2014 Oct;36(5):355-63.