产品说明书

Hesperidin methylchalcone

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Chemical Structure| 24292-52-2 同义名 : -
CAS号 : 24292-52-2
货号 : A549207
分子式 : C29H36O15
纯度 : 98%
分子量 : 624.587
MDL号 : MFCD00010438
存储条件：

粉末 Sealed in dry,2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 50 mg/mL(80.05 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Hesperidin methylchalcone, an orally active flavonoid, possesses analgesic, anti-inflammatory, and antioxidant effects. It demonstrates vasoprotective activity and inhibits oxidative stress, cytokine production, and NF-κB activation. Hesperidin methylchalcone is applicable in gout disease research[1][2].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.60mL

0.32mL

0.16mL

8.01mL

1.60mL

0.80mL

16.01mL

3.20mL

1.60mL
参考文献

[1]Bussmann AJC,et al. The Flavonoid Hesperidin Methyl Chalcone Targets Cytokines and Oxidative Stress to Reduce Diclofenac-Induced Acute Renal Injury: Contribution of the Nrf2 Redox-Sensitive Pathway. Antioxidants (Basel). 2022 Jun 27;11(7):1261.

[2]Ruiz-Miyazawa KW, et al. Hesperidin Methylchalcone Suppresses Experimental Gout Arthritis in Mice by Inhibiting NF-κB Activation. J Agric Food Chem. 2018 Jun 27;66(25):6269-6280.