产品说明书

Prim-O-glucosylcimifugin

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Chemical Structure| 80681-45-4 同义名 : 升麻苷 ;1''-O-Glucosylcimifugin;Cimifugin beta-D-glucopyranoside;PGCN;Cimifugin 7-glucoside
CAS号 : 80681-45-4
货号 : A540157
分子式 : C22H28O11
纯度 : 99%+
分子量 : 468.451
MDL号 : MFCD09037394
存储条件：

粉末 Sealed in dry,2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 145 mg/mL(309.53 mM)，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Prim-O-glucosylcimifugin is a natural product isolated and purified from the root of Saposhnikovia divaricata (Turcz.) Schischk., which can inhibit the proliferation of SMC(smooth muscle cell) stimulated by TNF-alpha, increase the proportion of G0/G1 phase.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.13mL

0.43mL

0.21mL

10.67mL

2.13mL

1.07mL

21.35mL

4.27mL

2.13mL
参考文献

[1]Song J, Zheng SR, et al. Pharmacokinetic Interaction of astragaloside IV with atractylenolide I and prim-O-glucosylcimifugin in male Sprague Dawley rats. Planta Med. 2014 Feb;80(2-3):187-92.

[2]Li Y, Zhao L, et al. Comparative pharmacokinetics of prim-O-glucosylcimifugin and cimifugin by liquid chromatography-mass spectrometry after oral administration of Radix Saposhnikoviae extract, cimifugin monomer solution and prim-O-glucosylcimifugin monomer solution to rats. Biomed Chromatogr. 2012 Oct;26(10):1234-40.