同义名 : | NSC248 | |
CAS号 : | 10163-15-2 | |
货号 : | A537600 | |
分子式 : | FNa2O3P | |
纯度 : | 95% | |
分子量 : | 143.95 | |
MDL号 : | MFCD00014248 | |
存储条件: |
粉末 Inert atmosphere,Room Temperature 液体 -20°C:3-6个月-80°C:12个月 |
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溶解度 : | - | |
动物实验配方: |
生物活性 | |||
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描述 | Sodium monofluorophosphate is a competitive inhibitor of pyruvate kinase and alkaline phosphatase with Ki of 3.4 mM and 69 μM, respectively, which also irreversibly inhibits phosphorylase phosphatase with Ki of 0.5 mM. |
临床研究 | |||||
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NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
NCT02924922 | Kidney Neoplasms | Not Applicable | Completed | - | Switzerland ... 展开 >> Klinik für Urologie, Kantonsspital Luzern Luzern, Switzerland, 6000 收起 << |
NCT02753075 | Dentin Sensitivity | Not Applicable | Completed | - | United States, Indiana ... 展开 >> GSK Investigational Site Fort Wayne, Indiana, United States, 46825 收起 << |
NCT03733210 | Squamous Cell Carcinoma of the... 展开 >> Head and Neck Carcinoma of the Head and Neck 收起 << | Phase 1 | Not yet recruiting | February 7, 2022 | United States, California ... 展开 >> Stanford Cancer Institute Palo Alto Not yet recruiting Palo Alto, California, United States, 94304 Contact: Eben L. Rosenthal 650-723-2967 elr@stanford.edu Principal Investigator: Eben L. Rosenthal 收起 << |
实验方案 | |||
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1mg | 5mg | 10mg | |
1 mM 5 mM 10 mM |
6.95mL 1.39mL 0.69mL |
34.73mL 6.95mL 3.47mL |
69.47mL 13.89mL 6.95mL |
参考文献 |
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[2]Pearce EI. Biochemistry of monofluorophosphate. Caries Res. 1983;17 Suppl 1:21-35. |