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Quillaic acid

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Chemical Structure| 631-01-6 同义名 : Quillaja sapogenin
CAS号 : 631-01-6
货号 : A535220
分子式 : C30H46O5
纯度 : 98%
分子量 : 486.683
MDL号 : MFCD22479218
存储条件：

粉末 Sealed in dry,Room Temperature

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 40 mg/mL(82.19 mM)，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Quillaic acid is the major aglycone of the widely studied saponins of the Chilean indigenous tree Quillaja saponaria Mol, and can elicit dose-dependent antinociceptive effects in two murine thermal models.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.05mL

0.41mL

0.21mL

10.27mL

2.05mL

1.03mL

20.55mL

4.11mL

2.05mL
参考文献

[1]Rodriguez-Diaz M, Delporte C, et al. Topical anti-inflammatory activity of quillaic acid from Quillaja saponaria Mol. and some derivatives. J Pharm Pharmacol. 2011 May;63(5):718-24.

[2]Arrau S, Delporte C, et al. Antinociceptive activity of Quillaja saponaria Mol. saponin extract, quillaic acid and derivatives in mice. J Ethnopharmacol. 2011 Jan 7;133(1):164-7.