Roburic acid

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Chemical Structure| 6812-81-3 同义名 : -
CAS号 : 6812-81-3
货号 : A534747
分子式 : C30H48O2
纯度 : 99%
分子量 : 440.701
MDL号 : MFCD09953817
存储条件：

Pure form Sealed in dry,2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 35 mg/mL(79.42 mM)，配合低频超声，并水浴加热至45℃助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Roburic acid, a natural product isolated and purified from the roots of Gentiana macrophylla, inhibits COX-1 and COX-2.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.27mL

0.45mL

0.23mL

11.35mL

2.27mL

1.13mL

22.69mL

4.54mL

2.27mL
参考文献

[1]Cao H, Yu R, et al. Discovery of cyclooxygenase inhibitors from medicinal plants used to treat inflammation. Pharmacol Res. 2010 Jun;61(6):519-24.

[2]Chen QL, Shi ZY, et al. [Studies on the chemical constituents in root of Gentiana macrophylla from Shaanxi] . Zhongguo Zhong Yao Za Zhi. 2005 Oct;30(19):1519-22.