Tipiracil

产品说明书

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Chemical Structure| 183204-74-2 同义名 : -
CAS号 : 183204-74-2
货号 : A532974
分子式 : C9H11ClN4O2
纯度 : 99%
分子量 : 242.662
MDL号 : MFCD17215839
存储条件：

Pure form Keep in dark place,Sealed in dry,Store in freezer, under -20°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

H2O: 1 mg/mL(4.12 mM)，配合低频超声助溶
动物实验配方：
生物活性
描述 Tipiracil is a thymidine phosphorylase (TPase) inhibitor.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

4.12mL

0.82mL

0.41mL

20.60mL

4.12mL

2.06mL

41.21mL

8.24mL

4.12mL
参考文献

[1]Raedler LA. Lonsurf (Trifluridine plus Tipiracil): A New Oral Treatment Approved for Patients with Metastatic Colorectal Cancer. Am Health Drug Benefits. 2016 Mar;9(Spec Feature):97-100.

[2]Lee SJ, Yeo JS, et al. Thymidine phosphorylase influences [(18)F] fluorothymidine uptake in cancer cells and patients with non-small cell lung cancer. Eur J Nucl Med Mol Imaging. 2014 Jul;41(7):1327-35.