产品说明书

Wedelolactone

Print
Chemical Structure| 524-12-9 同义名 : IKK Inhibitor II
CAS号 : 524-12-9
货号 : A523974
分子式 : C16H10O7
纯度 : 99%+
分子量 : 314.246
MDL号 : MFCD07778564
存储条件：

粉末 Sealed in dry,2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 120 mg/mL(381.87 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Wedelolactone, a natural compound derived from Chinese herbal medicine Eclipta prostrate L, is an anti-cancer agent for breast and prostate carcinomas in vitro and in vivo targeting multiple cellular proteins including androgen receptors, 5-lipoxygenase and topoisomerase IIα.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.18mL

0.64mL

0.32mL

15.91mL

3.18mL

1.59mL

31.82mL

6.36mL

3.18mL
参考文献

[1]Liu YQ, Zhan LB, et al. Inhibitory effect of Ecliptae herba extract and its component wedelolactone on pre-osteoclastic proliferation and differentiation. J Ethnopharmacol. 2014 Nov 18;157:206-11.

[2]Nehybova T, Smarda J, et al. Wedelolactone induces growth of breast cancer cells by stimulation of estrogen receptor signalling. J Steroid Biochem Mol Biol. 2015 Aug;152:76-83.