产品说明书

Eupalinolide B

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Chemical Structure| 877822-41-8 同义名 : -
CAS号 : 877822-41-8
货号 : A519889
分子式 : C24H30O9
纯度 : 98%
分子量 : 462.49
MDL号 : MFCD23379927
存储条件：

粉末 Keep in dark place,Sealed in dry,Store in freezer, under -20°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(227.03 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Eupalinolide A is a natural product isolated and purified from the herbs of Eupatorium lindleyanum DC.. Eupalinolide A and Eupalinolide B induce the expression of HSP70 via the activation of HSF1 by inhibiting the interaction between HSF1 and HSP90, and also could be beneficial for use in cosmetics and medicines as a consequence of their inhibitory action on UV-induced skin damage and melanin production.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.16mL

0.43mL

0.22mL

10.81mL

2.16mL

1.08mL

21.62mL

4.32mL

2.16mL
参考文献

[1]Zhang J, Zhao F, et al. Pharmacokinetics of eupalinolide A, eupalinolide B and hyperoside from Eupatorium lindleyanum in rats by LC/MS/MS. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Jul 15;995-996:1-7.

[2]Yan G, Ji L, et al. Preparative isolation and purification of three sesquiterpenoid lactones from Eupatorium lindleyanum DC. by high-speed counter-current chromatography. Molecules. 2012 Jul 27;17(8):9002-9.