产品说明书

LIMK-IN-1

Print
Chemical Structure| 1116571-01-7 同义名 : -
CAS号 : 1116571-01-7
货号 : A511851
分子式 : C20H21BrN8
纯度 : 95%
分子量 : 453.338
MDL号 : MFCD18642632
存储条件：

粉末 Sealed in dry,2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 LIMK-IN-1 is a LIM-Kinase (LIMK) inhibitor, with IC50s of 0.5 nM for LIMK1 and 0.9 nM for LIMK2. It is useful in the study of ocular hypertension and related glaucoma[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.21mL

0.44mL

0.22mL

11.03mL

2.21mL

1.10mL

22.06mL

4.41mL

2.21mL
参考文献

[1]Harrison BA, etAl. Novel class of LIM-kinase 2 inhibitors for the treatment of ocular hypertension and associated glaucoma. J Med Chem. 2009 Nov 12;52(21):6515-8.