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Eriodictyol-7-O-glucoside

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Chemical Structure| 38965-51-4 同义名 : Eriodictyol 7-O-β-D-glucoside;7-O-β-D-Glucopyranosyl-eriodictyol;(2S)-Eriodictyol 7-O-β-D-glucopyranoside
CAS号 : 38965-51-4
货号 : A509884
分子式 : C21H22O11
纯度 : 98%
分子量 : 450.393
MDL号 : MFCD18632528
存储条件：

粉末 Keep in dark place,Inert atmosphere,2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(233.13 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Eriodictyol-7-O-glucoside, a natural product isolated and purified from the herbs of Dracocephalum rupestre, can activate Nrf2/ARE signaling, directly associated with its neuroprotection against oxidative stress-induced ischemic, suggesting that targeting the Nrf2/ARE pathway may be a promising approach for therapeutic intervention in stroke.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.22mL

0.44mL

0.22mL

11.10mL

2.22mL

1.11mL

22.20mL

4.44mL

2.22mL
参考文献

[1]Jing X, Ren D, et al. Eriodictyol-7-O-glucoside activates Nrf2 and protects against cerebral ischemic injury. Toxicol Appl Pharmacol. 2013 Dec 15;273(3):672-9.

[2]Hu Q, Zhang DD, et al. Eriodictyol-7-O-glucoside, a novel Nrf2 activator, confers protection against cisplatin-induced toxicity. Food Chem Toxicol. 2012 Jun;50(6):1927-32.