产品说明书
RGX-104 HCl
 |
同义名 : | Abequolixron hydrochloride;Abequolixron;RGX-104;RGX-104 hydrochloride |
| CAS号 : | 610318-03-1 | |
| 货号 : | A508736 | |
| 分子式 : | C34H34Cl2F3NO3 | |
| 纯度 : | 99%+ | |
| 分子量 : | 632.54 | |
| MDL号 : | MFCD31657403 | |
| 存储条件： |
粉末 Inert atmosphere,Room Temperature 液体 -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 145 mg/mL(229.23 mM)，配合低频超声，并水浴加热至45℃助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
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| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | RGX-104 is a small-molecule LXR agonist that modulates innate immunity via transcriptional activation of the ApoE gene. | ||
| 临床研究 | |||||
|---|---|---|---|---|---|
| NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
| NCT02922764 | Malignant Neoplasms | Phase 1 | Recruiting | October 2019 | United States, California ... 展开 >> Cedars-Sinai Medical Center Recruiting Los Angeles, California, United States, 90048 Contact: Monica Mita, MD 310-248-6729 Monica.Mita@cshs.org University of California, Los Angeles Recruiting Los Angeles, California, United States, 90095 Contact: Bartosz Chmielowski, MD, PhD 310-586-2650 BChmielowski@mednet.ucla.edu United States, Colorado Sarah Cannon Research Institute Recruiting Denver, Colorado, United States, 80218 Contact: Gerald Falchook, MD 281-221-0693 gerald.falchook@scresearch.net United States, New Mexico University of New Mexico Comprehensive Cancer Center Recruiting Albuquerque, New Mexico, United States, 87106 Contact: Olivier Rixe, MD 505-272-4946 United States, New York Columbia University Medical Center Recruiting New York, New York, United States, 10032 Contact: Emerson Lim, MD 202-305-5874 el2342@cumc.columbia.edu Memorial Sloan Kettering Cancer Center Recruiting New York, New York, United States, 10065 Contact: Michael Postow, MD 646-888-4589 postowm@mskcc.org United States, Tennessee The Sarah Cannon Research Institute Recruiting Nashville, Tennessee, United States, 37203 Contact: Erika Hamilton, MD 615-329-7274 ehamilton@tnonc.com United States, Texas Mary Crowley Cancer Research - Medical City Recruiting Dallas, Texas, United States, 75230 Contact: James F Strauss, MD 214-739-4175 The University of Texas MD Anderson Cancer Center Recruiting Houston, Texas, United States, 77030 Contact: Shubham Pant, MD 713-563-0181 SPant@mdanderson.org 收起 << |
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
1.58mL 0.32mL 0.16mL |
7.90mL 1.58mL 0.79mL |
15.81mL 3.16mL 1.58mL |
