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Hinokiflavone

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Chemical Structure| 19202-36-9 同义名 : 日本扁柏黄酮
CAS号 : 19202-36-9
货号 : A508349
分子式 : C30H18O10
纯度 : 99%+
分子量 : 538.458
MDL号 : MFCD00017455
存储条件：

粉末 Sealed in dry,Store in freezer, under -20°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 50 mg/mL(92.86 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO

无水乙醇: 2 mg/mL(3.71 mM)，配合低频超声助溶，注意：无水乙醇开封后，易挥发，也会吸收空气中的水分，导致溶解能力下降，请避免使用开封较久的乙醇
动物实验配方：
生物活性
描述 Hinokiflavone, a natural product isolated and purified from the leaves of Platycladus orientalis, with significant cytotoxicity, can inhibit the activity of MMP-9.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.86mL

0.37mL

0.19mL

9.29mL

1.86mL

0.93mL

18.57mL

3.71mL

1.86mL
参考文献

[1]Kalva S, Azhagiya Singam ER, et al. Discovery of potent inhibitor for matrix metalloproteinase-9 by pharmacophore based modeling and dynamics simulation studies. J Mol Graph Model. 2014 Apr;49:25-37.

[2]Lin YM, Chen FC, Lee KH. Hinokiflavone, a cytotoxic principle from Rhus succedanea and the cytotoxicity of the related biflavonoids. Planta Med. 1989 Apr;55(2):166-8.