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Mutant IDH1 inhibitor

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Chemical Structure| 1429180-08-4 同义名 : -
CAS号 : 1429180-08-4
货号 : A501742
分子式 : C25H34N6O3
纯度 : 99%
分子量 : 466.576
MDL号 : MFCD28167739
存储条件：

粉末 Keep in dark place,Sealed in dry,2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 35 mg/mL(75.01 mM)，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 The mutant IDH1 inhibitor is highly effective against IDH1 R132H and is employed in the treatment of diseases or conditions linked to this mutant IDH protein, including but not limited to cell-proliferation disorders such as cancer [1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.14mL

0.43mL

0.21mL

10.72mL

2.14mL

1.07mL

21.43mL

4.29mL

2.14mL
参考文献

[1]3-Pyrimidin-4-yl-oxazolidin-2-ones as inhibitors of mutant IDH and their preparation. Patent WO 2013046136 A1 20130404