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Azilsartan medoxomil monopotassium

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Chemical Structure| 863031-24-7 同义名 : Azilsartan kamedoxomil;TAK 491 monopotassium
CAS号 : 863031-24-7
货号 : A496199
分子式 : C30H23KN4O8
纯度 : 99%
分子量 : 606.624
MDL号 : MFCD24849277
存储条件：

粉末 Inert atmosphere,2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 Azilsartan medoxomil is an orally administered angiotensin II receptor type 1 antagonist with IC50 of 0.62 nM, which used in the treatment of adults with essential hypertension.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.65mL

0.33mL

0.16mL

8.24mL

1.65mL

0.82mL

16.48mL

3.30mL

1.65mL
参考文献

[1]Kajiya T, Ho C, Wang J, Molecular and cellular effects of azilsartan: a new generation angiotensin II receptor blocker. J Hypertens. 2011 Dec;29(12):2476-83.