生物活性 | |||
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描述 | 1-Ethynylpyrene is an aryl acetylenic inhibitor of cytochromes P450 1A1, 1A2, and 2B1, demonstrating IC50s of 0.18, 0.32, and 0.04 μM, respectively[1]. 1-Ethynylpyrene functions as a click chemistry reagent, featuring an alkyne group capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing azide groups. |
实验方案 | |||
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1mg | 5mg | 10mg | |
1 mM 5 mM 10 mM |
4.42mL 0.88mL 0.44mL |
22.10mL 4.42mL 2.21mL |
44.19mL 8.84mL 4.42mL |
参考文献 |
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