Methyl p-hydroxyphenyllactate

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Chemical Structure| 51095-47-7 同义名 : -
CAS号 : 51095-47-7
货号 : A493389
分子式 : C10H12O4
纯度 : 98+%
分子量 : 196.2
MDL号 : -
存储条件：

Pure form

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 Methyl p-hydroxyphenyllactate, a natural product isolated and purified from the herbs of Crepis crocea., can suppress the cellular proliferation of estrogen-sensitive MCF-7 breast cancer cells in vitro and to suppress the growth of rat uteri in vivo, high affinity of MeHPLA for the type II estrogen binding site (EBS) suggests that this interaction is responsible for the observed suppression of cell growth.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

5.10mL

1.02mL

0.51mL

25.48mL

5.10mL

2.55mL

50.97mL

10.19mL

5.10mL
参考文献

[1]Li YY, Peng ZQ, et al. [Chemical constituents from Crepis crocea] . Zhongguo Zhong Yao Za Zhi. 2015 Oct;40(19):3800-4. Chinese.

[2]Pretlow L, Williams R, Elliott M. Type II estrogen binding site agonist: synthesis and biological evaluation of the enantiomers of methyl-para-hydroxyphenyllactate (MeHPLA). Chirality. 2003 Oct;15(8):674-9.