产品说明书
SARS-CoV-2-IN-14
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同义名 : | - |
| CAS号 : | 22203-98-1 | |
| 货号 : | A490995 | |
| 分子式 : | C13H9Cl2NO2 | |
| 纯度 : | 95% | |
| 分子量 : | 282.122 | |
| MDL号 : | MFCD11521629 | |
| 存储条件： |
粉末 Sealed in dry,Room Temperature 液体 -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 250 mg/mL(886.14 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
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| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | SARS-CoV-2-IN-14, another effective SARS-CoV-2 inhibitor with an IC50 of 0.39 μM, also derives from a niclosamide analogue. It exhibits increased stability in human plasma and liver S9 enzyme assays than niclosamide, which may improve its bioavailability and prolong its half-life upon oral administration[1]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
3.54mL 0.71mL 0.35mL |
17.72mL 3.54mL 1.77mL |
35.45mL 7.09mL 3.54mL |
| 参考文献 |
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