产品说明书

Isofraxidin

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Chemical Structure| 486-21-5 同义名 : 异秦皮啶
CAS号 : 486-21-5
货号 : A480950
分子式 : C11H10O5
纯度 : 99%+
分子量 : 222.194
MDL号 : MFCD00221757
存储条件：

粉末 Keep in dark place,Inert atmosphere,Room temperature

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 250 mg/mL(1125.14 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Isofraxidin, a natural product isolated and purified from the herbs of Sarcandra glabra (Thunb.) Nakai, possesses significant analgesic and anti-inflammatory activities that may be mediated through the regulation of pro-inflammatory cytokines, TNF-α and the phosphorylation of p38 and ERK1/2.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

4.50mL

0.90mL

0.45mL

22.50mL

4.50mL

2.25mL

45.01mL

9.00mL

4.50mL
参考文献

[1]Liu L, Mu Q, et al. Isofraxidin protects mice from LPS challenge by inhibiting pro-inflammatory cytokines and alleviating histopathological changes. Immunobiology. 2015 Mar;220(3):406-13.

[2]Niu X, Wang Y, et al. Protective effects of Isofraxidin against lipopolysaccharide-induced acute lung injury in mice. Int Immunopharmacol. 2015 Feb;24(2):432-9.