Fidarestat
产品说明书
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同义名 : | SNK 860 |
| CAS号 : | 136087-85-9 | |
| 货号 : | A474076 | |
| 分子式 : | C12H10FN3O4 | |
| 纯度 : | 98% | |
| 分子量 : | 279.224 | |
| MDL号 : | MFCD00919183 | |
| 存储条件： |
Pure form Inert atmosphere, store in freezer, under -20°C In solvent -20°C:3-6个月-80°C:12个月 |
|
| 溶解度 : |
DMSO: 250 mg/mL(895.34 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
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| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Fidarestat is an inhibitor of aldose reductase, with IC50s of 26 nM, 33 μM, and 1.8 μM for aldose reductase, AKR1B10 and V301L AKR1B10, respectively; Fidarestat has the potential to treat diabetic disease. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
3.58mL 0.72mL 0.36mL |
17.91mL 3.58mL 1.79mL |
35.81mL 7.16mL 3.58mL |
