产品说明书

	同义名 :	Spermatheridine;VLT045
	CAS号 :	475-75-2
	货号 :	A470859
	分子式 :	C17H9NO3
	纯度 :	98+%
	分子量 :	275.258
	MDL号 :	MFCD00936501
	存储条件：	粉末 Sealed in dry,2-8°C 液体 -20°C:3-6个月-80°C:12个月
	溶解度 :	-
	动物实验配方：

生物活性
描述	Liriodenine, a natural product isolated and purified from the barks of Liriodendron chinense (Hemsl.) Sarg., with anti-fungal activity, inhibits progression of the CAOV-3 cell cycle in S phase and exhibits potent antitumor activities in laryngocarcinoma HEp-2 cells, in vitro and in vivo, via the upregulation of p53 expression.

实验方案
	1mg	5mg	10mg
1 mM 5 mM 10 mM	3.63mL 0.73mL 0.36mL	18.16mL 3.63mL 1.82mL	36.33mL 7.27mL 3.63mL

参考文献

[1]Li L, Xu Y, Wang B. Liriodenine induces the apoptosis of human laryngocarcinoma cells via the upregulation of p53 expression. Oncol Lett. 2015 Mar;9(3):1121-1127. [2]Nordin N, Majid NA, et al. Liriodenine, an aporphine alkaloid from Enicosanthellum pulchrum, inhibits proliferation of human ovarian cancer cells through induction of apoptosis via the mitochondrial signaling pathway and blocking cell cycle progression. Drug Des Devel Ther. 2015 Mar 10;9:1437-48.