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PKR activator 3

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Chemical Structure| 1628428-01-2 同义名 : PKR-IN-2
CAS号 : 1628428-01-2
货号 : A464711
分子式 : C24H28N4O4S
纯度 : 99%+
分子量 : 468.568
MDL号 : MFCD29472293
存储条件：

粉末 Sealed in dry,Store in freezer, under -20°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 50 mg/mL(106.71 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 PKR Activator 3 is an activator for the pyruvate kinase isoform PKR, contributing to research on diseases associated with PKR function, such as cancer, diabetes, obesity, autoimmune diseases, and benign prostatic hyperplasia[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.13mL

0.43mL

0.21mL

10.67mL

2.13mL

1.07mL

21.34mL

4.27mL

2.13mL
参考文献

[1]Popovici-Muller, et al. Preparation of N-(piperidinecarbonylphenyl) sulfonamide compounds as pyruvate kinase modulators. From PCT Int. Appl. (2014), WO2014139144A1 20140918.